OUR BLOG

Can the Regular Use of NSAIDs Inhibit Ovulation & Reduce Fertility?

 

For many people the world over the regular use of painkillers is almost a habitual process, and as with all medication that alleviates pain, there is a side effect, however recent studies have highlighted a somewhat surprising and revelatory side-effect with the regular use of one of the world’s largest pain killer groups – NSAIDs. Nonsteroidal anti-inflammatory drugs often used in the treatment of pain, migraine, muscle and joint pains, such as ibuprofen, naproxen, diclofenac and indomethacin (to name but a few) have been successfully shown to inhibit ovulation and reduce progesterone levels in women, with a tangible reduction in fertility that happens with only 10 days of continuous use!

 

The study undertaken by leading researcher Sami Salman M.D. confirms that a woman will not fall pregnant if she continues to take NSAIDs as it has a direct negative influence on fertility in women who are experiencing difficulty conceiving. However, there is  good news! This substantial and rapid reduction in fertility is absolutely reversible by stopping the use of NSAIDs.

 

This groundbreaking study included 39 women of childbearing age who were experiencing minor back pain. And as the research  commenced each of the 39 woman had an ultrasound to assess the dominant follicle’s diameter, ovary size and endothelial thickness. Her progesterone levels were also tested. They were then given either:

 

  • Diclofenac – 100mg per day.
  • Naproxen – 500mg twice daily.
  • Etoricoxib – 90mg per day.
  • Placebo.

 

The study commenced treatment on day 10 of the menstrual cycle, and after 10 days of continuous treatment, the participants once again underwent an ultrasound and updated assessment of their progesterone levels. The research showed that all of the women who were given the placebo successfully ovulated within this timespan, however, the women who were given NSAIDs experienced a substantially lower frequency of ovulation. As we know ovulation occurs when the dominant follicle ruptures, in this study the dominant follicle did not rupture in 75% of all women taking diclofenac, 25% of women taking naproxen and 33% taking etoricoxib. It also showed without a doubt that the women taking NSAIDs had much lower levels of progesterone than those women who were taking placebo. Therefore reducing her fertility and chances of falling pregnant.

 

On a positive note, half of the women involved in the study discontinued the use of NSAIDs and returned to be tested 4 weeks later, all of these women ovulated normally in their next menstrual cycle. This is one of the many studies currently underway, highlighting the risk of regular NSAIDs use and the role it plays in reducing a woman's fertility. If you are experiencing difficulty in trying-to-conceive and the regulation of your menstrual cycle and fertility window (check out our Ovulation Calculator), and if you currently use NSAIDs frequently we recommend that you consult with your GP for more ‘fertility-friendly’ pain relief options.

 

For more options in detecting your fertility window and enhancing you fertility, click fertilitystore.ie for more information. Choose from our selection of Ovulation and Fertility testing kits.

 

 

 

LATEST POSTS

  • Am I Infertile? Am I Infertile?
  • Getting Pregnant Myths & Facts Getting Pregnant Myths & Facts
  • How Does My Menstrual Cycle Work? How Does My Menstrual Cycle Work?
  • Preconception Check Up? Have You Had Yours? Preconception Check Up? Have You Had Yours?
  • What if I have irregular periods? What if I have irregular periods?
  • Why Getting Pregnant Should Be Fun! Why Getting Pregnant Should Be Fun!
  • Your Getting Pregnant Checklist  Your Getting Pregnant Checklist
  • Timing: Getting Pregnant Faster! Timing: Getting Pregnant Faster!
  • Weird & Wonderful Ways Ovulation Can Affect Your Body Weird & Wonderful Ways Ovulation Can Affect Your Body
  • Can A Woman Become Pregnant During Her Period? Can A Woman Become Pregnant During Her Period?
  • What is Ovulatory Dysfunction? What is Ovulatory Dysfunction?
  • How to Normalise Irregular Cycles & Boost your Fertility! How to Normalise Irregular Cycles & Boost your Fertility!
  • Say No to Normal Lubricants & Check your Cervical Mucus! Say No to Normal Lubricants & Check your Cervical Mucus!
  • Know your Fertile Days! Know your Fertile Days!
  • Can the Regular Use of NSAIDs Inhibit Ovulation & Reduce Fertility? Can the Regular Use of NSAIDs Inhibit Ovulation & Reduce Fertility?
  • Male Infertility Fact or Fiction? Male Infertility Fact or Fiction?
  • Fertility Myths Uncovered! Fertility Myths Uncovered!
  •  How to use your  Digital Basal Thermometer How to use your Digital Basal Thermometer
  •  5 Signs You Are Fertile Now! 5 Signs You Are Fertile Now!
  • What not to say to someone with fertility issues! What not to say to someone with fertility issues!
  • Acupuncture & Fertility Acupuncture & Fertility
  • 5 Environmental Toxins That May Harm Your Fertility 5 Environmental Toxins That May Harm Your Fertility
  • Is it Time for Baby No.2? Is it Time for Baby No.2?